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Image Search Results
Journal: bioRxiv
Article Title: Deletion of absent in melanoma (AIM) 2 gene alters bone morphology
doi: 10.1101/2024.01.05.574199
Figure Lengend Snippet: Cancellous (trabecular) bone morphology was determined at the lumbar vertebra-4 (L4) including, (A) trabecular bone volume per total volume (BV/TV), (B) bone mineral density (BMD), (C) trabecular bone thickness (Tb.Th), and (D) trabecular number (Tb.N). 5-months old WT (n=5), 15-months old WT (n=5), 5-months old Aim2KO (n=6), 15-months old Aim2KO (n=7) (E) Cathepsin K and TRAP expression levels were determined in bone marrow of 5-months old mice. WT (n=8), Aim2KO (n=12). (F) Sections of L4 immunostained with cathepsin K antibody. The number of cathepsin K positive cells on bone surface was calculated. WT (n=5), Aim2KO (n=6). Significance was determined by 2way ANOVA (genotype/age).). *p<0.05, **p<0.01.
Article Snippet: Immunohistochemistry was performed as described in our recent papers [ , ] using antigen unmasking solutionn (H-3300; Vector Laboratories, CA, USA),
Techniques: Expressing